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Symbol
Name
ID
Sox2
SRY (sex determining region Y)-box 2
MGI:98364
Phenotype annotations related to reproductive system
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Hypogonadotropic hypogonadism
Hypospadias
Hypoplasia of penis
Micropenis
Cryptorchidism
Disease(s) Associated with SOX2
syndromic microphthalmia 3

Mouse Phenotypes
oligozoospermia
abnormal seminiferous tubule morphology
small testis
reduced male fertility
Availability Mouse Genotype
Sox2tm1Rlb/Sox2+ !

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory